This hole is actually a break in the moist tissue (mucous membrane) that lines the mouth. Mucositis causes painful swelling of the mouth and tongue and can lead to bleeding, pain, and mouth ulcers. Quitting smoking has numerous health benefits, including restoring taste you lost to the habit. Sugar is an added ingredient in many types of drug products, from vitamins and cough drops to antacids and syrup-based medications. Chemotherapy drugs that cause mucositis can cause mouth sores to develop. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Good oral hygiene and more frequent visits to the dentist (perhaps every three months) can help lower your chances of developing this condition. Be sure to try new foods when you're feeling good so you don't develop more food dislikes. AUTOHALER? and Tablets, PROTOPIC® – Fujisawa (tacrolimus) Ointment 0.03% and 0.1%, REFACTO® – Wyeth-Ayerst Antihemophilic Factor, Recombinant, RELAFEN® – GlaxoSmithKline brand of nabumetone tablets, RELPAX® – Pfizer (eletriptan hydrobromide) Tablets, RESCRIPTOR® – Pfizer brand of delavirdine mesylate tablets, REYATAZ® – Bristol-Myers Squibb (atazanavir sulfate) Capsules, SALAGEN® – MGI (pilocarpine hydrochloride) Tablets, SANDOSTATIN LAR® DEPOT – Novartis (octreotide acetate for injectable suspension), SEROQUEL® – AstraZeneca (quetiapine fumarate), SPECTRACEF® – Purdue Pharmaceutical cefditoren pivoxil Tablets, SPORANOX® – Janssen (itraconazole) Oral Solution, STALEVO® – Novartis (carbidopa, levodopa and entacapone) Tablets, STRIANT® – Columbia (testosterone buccal system) mucoadhesive, SULAR® – First Horizon (Nisoldipine) Extended Release Tablets, SURMONTIL® – Odyssey (trimipramine maleate), SUSTIVA® – Bristol-Myers Squibb (efavirenz) Capsules and tablets, SYMBYAX? Some just have a weird taste but others can change the taste of everything you eat for hours afterword giving things a bitter, metallic taste. Having existing dental plaque also raises your risk. Journal of the American Dental Association, June 2005. These drugs were representatives of the following classifications: psychotropic, cardiovascular, analgesic, anti-inflammatory, antihistamine, sedatives, antiemetic, antimicrobial, and antiviral. When the teeth grow in, they are a yellowish-color, and they gradually turn brown when exposed to sunlight. Or use sports drinks to make frozen popsicles. Chemotherapy medicines that can cause mucositis include: A mouth ulcer refers to an open (ulcerated) sore that occurs inside the mouth or on the tongue. Medications can affect the taste buds and ion channels in taste-bud cell membranes involved in stimulus transduction. Then it's time to take another capsule. Extended-ReleaseTablets – Andrx Labs (Lovastatin), AMERGE® – GlaxoSmithKline (naratriptan hydrochloride) Tablets, ANZEMET® Injection – Aventis (dolasetron mesylate injection), ANZEMET® – Aventis (dolasetron mesylate) Tablets, AQUAMEPHYTON® – Merck (Phytonadione) Aqueous Colloidal Solution of Vitamin K1 Injection, ASACOL® – Procter & Gamble Pharmaceuticals (mesalamine) Delayed-Release Tablets, ATROVENT® – Boehringer Ingelheim (ipratropium bromide) Nasal Spray, AVINZA® – Ligand (morphine sulfate extended-release Capsules), AXERT® – Ortho-McNeil (almotriptan malate) Tablets, AZACTAM® – Elan (aztreonam for injection), BACTROBAN NASAL® – GlaxoSmithKline brand of mupirocin calcium ointment, BEXTRA® – Pharmacia & Upjohn valdecoxib tablets, BIAXIN® GRANULES (clarithromycin for oral suspension), BICILLIN® L-A – King (penicillin G benzathine suspension) INJECTION FOR DEEP IM INJECTION, BREVIBLOC – Baxter health care, Concentrate, Injection, Premixed Injection, Double Strength Injection, Double Strength Premixed Injection, BRIMONIDINE TARTRATE – Bausch & Lomb Ophthalmic Solution 0.2% STERILE OPHTHALMIC SOLUTION, CADUET® – Pfizer (amlodipine besylate/atorvastatin calcium), CAMPRAL® – Forest (acamprosate calcium) Delayed-Release Tablets, CARTEOLOL HYDROCHLORIDE – Bausch & Lomb Ophthalmic Solution USP, 1% STERILE OPHTHALMIC SOLUTION, CEDAX® – Shionogi (ceftibuten Capsules) and (ceftibuten for oral suspension) FOR ORAL USE ONLY, CELEXA® – Forest (citalopram hydrobromide) Tablets/Oral Solution, CIPRO® XR – Bayer (ciprofloxacin* extended-release tablets), CIPRODEX® – Alcon (ciprofloxacin 0.3% and dexamethasone 0.1%) Sterile Otic Suspension, COLAZAL® – Salix (balsalazide disodium) Capsules, COMBIVENT® – Boehringer Ingelheim (ipratropium bromide and albuterol sulfate) Inhalation Aerosol Bronchodilator Aerosol, COPAXONE® – Teva Neuroscience (glatiramer acetate injection), COUMADIN – Bristol-Myers Squibb Tablets and Injection, COZAAR® – Merck (losartan potassium tablets), CRIXIVAN® – Merck (INDINAVIR SULFATE) Capsules, CUBICIN® – Cubist (daptomycin for injection), CYTOVENE®-IV – Roche Laboratories (ganciclovir sodium for injection), CYTOVENE® – Roche Laboratories (ganciclovir Capsules), CYTOVENE®-IV – Roche Laboratories (ganciclovir sodium for injection) FOR INTRAVENOUS INFUSION, CYTOVENE® (ganciclovir Capsules) FOR ORAL ADMINISTRATION, DANTRIUM® – Procter & Gamble Pharmaceuticals (dantrolene sodium) Capsules, DENAVIR® – Novartis Consumer, a brand of penciclovir cream, 1%, DEPAKOTE® ER – Abbott (divalproex sodium) Extended-ReleaseTablets, DIFLUCAN® – Pfizer (Fluconazole Tablets) (Injection, Oral Suspension and Tablets), DILAUDID® – Abbott (hydromorphone hydrochloride) Dose Vials, Oral Liquid, Powder, Suppositories, Tablets and injection, DILAUDID® – Abbott (hydromorphone hydrochloride), DIPRIVAN® – AstraZeneca (propofol) Injectable Emulsion FOR IV ADMINISTRATION, DOXIL® – Tibotec (doxorubicin HCl liposome injection) FOR INTRAVENOUS INFUSION ONLY, DUONEB® – Dey (Ipratropium Bromide 0.5 mg/Albuterol Sulfate 3.0 mg*) Inhalation Solution, EFFEXOR® – Wyeth-Ayerst (venlafaxine hydrochloride) Tablets, XR Capsules, ELDEPRYL® – Somerset (SELEGILINE HYDROCHLORIDE) Capsules, ELIGARD® 7.5 mg – Sanofi-Synthelabo (leuprolide acetate for injectable suspension), ESKALITH® – GlaxoSmithKline (lithium carbonate) Capsules, ESKALITH CR® (lithium carbonate) Controlled-Release Tablets, EVOXAC® – Daiichi (cevimeline hydrochloride) Capsules, EXELON® – Novartis (rivastigmine tartrate) Capsules, EXELON® – Novartis (rivastigmine tartrate) Oral Solution, FACTIVE® – Ocient (gemifloxacin mesylate) Tablets, FLONASE® – GlaxoSmithKline (fluticasone propionate) Nasal Spray, FLOXIN® – Ortho-McNeil (ofloxacin) tablets, FLUMADINE® – Forest (rimantadine hydrochloride tablets) Tablets and SYRUP, FML® – Allergan (fluorometholone ophthalmic suspension), FML FORTE® – Allergan (fluorometholone ophthalmic suspension), FOSAMAX® – Merck (alendronate sodium) Tablets and Oral Solution, GABITRIL® – Cephalon (tiagabine hydrochloride) Tablets, GASTROCROM® – Celltech (cromolyn sodium) Oral Concentrate, HIVID® – Roche Laboratories (zalcitabine) Tablets, HYZAAR® 50-12.5 – Merck (losartan potassium-hydrochlorothiazide) tablets, INFERGEN® – InterMune (Interferon alfacon-1), INVANZ® – Merck (ertapenem for injection), INVIRASE® – Roche Laboratories (saquinavir mesylate) Capsules, JANTOVEN? Testing should be considered if the patient is not meeting goals of rehabilitation, because altered taste perception may lead to depression, weight loss, and malnutrition, all of which may act to confound rehabilitation efforts.. Rinse your mouth out after using such products, or ask your doctor or pharmacist if there is a sugar-free alternative. Some medicines that list dry mouth as a side effect include: Dry mouth can be a bothersome problem. Photo: AdobeStock/Voyagerix The link to diabetes. However, certain citrus fruits, particularly grapefruit, can affect the way some medications work so check with your doctor or pharmacist first. Mouth sores may also be called canker sores. However, many times, the benefits of using a medicine outweigh the risks and discomfort of dry mouth. They include: Corticosteroids (used to treat inflammation). Ciancio, S. Journal of the American Dental Association, vol 135. Nelson, R. Archives of Dermatology. click here. Usually the taste changes are temporary and go away when you stop taking the medicine. It only causes a change in tooth color if you take the medicine before the primary or secondary teeth come in. Some medications can cause a buildup of gum tissue, a condition called "gingival overgrowth." Some drugs can make food taste different, or they can cause a metallic, salty, or bitter taste in your mouth. If you’re being treated for cancer, your sense of taste might be thrown off … Your sense of taste should return to normal after treatment ends, but it may take some time. There are also antidepressants, anticonvulsants, antacids, anticholinergics and antidiabetic medications that can cause taste disturbances, according to Junior Dentist. When a person takes tetracycline, some of the medicine settles into the calcium that the body uses to build teeth. A sense of taste that is compromised could also affect a person’s appetite and enjoyment of their food. Saliva substitutes, such as those you spray into your mouth, may also be effective. Taste changes are especially common among elderly patients who take multiple medications. You are born with 9,000 taste buds, which work in tandem with your sense of smell as your sense of taste relies primarily on odors. Drugs that Change Taste. Noticing things smell different or certain smells are stronger; Having a bitter or metallic taste in the mouth. Some pain medications also can affect your sense of taste and smell. Duthie, E.H.   Some people find that their taste buds are hypersensitive when they begin to taste things normally again, while other people find it to be a gradual process. Between the ages of 40 and 50, the number of taste buds decreases, and the rest begin to shrink, losing mass vital to their operation. At the first sign of a rash, stop taking the drug and see your doctor to determine whether it is the beginning of one of the severe skin reactions. In severe cases, excess fluoride (called fluorosis) can lead to permanently stained brown teeth. The sense of taste is an oral chemical sense in mammals that is involved in the choice of foods. Certain drugs used to treat high blood pressure, such as amlodipine, diltiazem, and some ACE inhibitors, can interfere with smell. – 3M (flecainide acetate) Tablets, TIMENTIN® – GlaxoSmithKline (sterile ticarcillin disodium and clavulanate potassium) for Intravenous Administration ADD-VANTAGE® VIAL, TINDAMAX? Facial swelling, difficulty breathing or a feeling of your throat closing may be signs of a serious allergic reaction and require emergency care. Mucositis is a common side effect of chemotherapy treatment. Some people call it medicine mouth, the drug companies refer to it as Taste perversion. Taste Changes Should Be Temporary . Use sugar-free candies and gum to get rid of bad tastes: mints, zinc lozenges, gum, etc. Some drugs can reduce the amount of saliva in your mouth, causing an uncomfortably dry mouth (xerostomia). More than 400 medications are known to cause dry mouth. (3M) (pirbuterol acetate inhalation aerosol) For Oral Inhalation Only, MAXZIDE® and MAXZIDE® – Mylan Tablets BRAND OF (TRIAMTERENE AND HYDROCHLOROTHIAZIDE), METROGEL-VAGINAL® – 3M (metronidazole vaginal gel) 0.75% Vaginal Gel, MIACALCIN® – Novartis (calcitonin-salmon) Nasal Spray, MIRAPEX® – Pharmacia & Upjohn pramipexole dihydrochloride tablets, MIRAPEX® – Boehringer Ingelheim (pramipexole dihydrochloride), MOBIC® – Boehringer Ingelheim (meloxicam), MS CONTIN® – Purdue Frederick (Morphine Sulfate Controlled-Release) Tablets, MSIR – Purdue Frederick, Oral Solution Concentrate and Oral Tablets, NASONEX® – Schering (mometasone furoate monohydrate) Nasal Spray, NEORAL® SOFT GELATIN Capsules – Novartis (cyclosporine Capsules) MODIFIED, NEORAL® Oral Solution (cyclosporine oral solution) MODIFIED, NEURONTIN – Parke-Davis, Capsules, Tablets, and Oral Solution, NIPENT® – SuperGen (pentostatin for injection), NORVASC® – Pfizer (amlodipine besylate) Tablets), ORAMORPH® SR – AAI Pharma (MORPHINE SULFATE) Sustained-Release Tablets, OXYCONTIN® – Purdue Pharma (Oxycodone HCl Controlled-Release) Tablets, PARCOPA? August 2006. I could not find research about directly re-stimulating the taste buds, but at the very least, supporting the person … Drink tart juices to “mask” the taste of medicine mouth: cranberry, lemonade, pineapple juice, orange juice, etc. Lemons are great for the senses and your taste buds could perk up with a slice of the zesty fruit. Other medicines are believed to affect materials in or on existing teeth, causing staining. Some medications can also affect our sense of smell or the amount of saliva that we produce — both of which are factors that can affect the taste of food just as much as our taste buds … Tetracycline, however, does not cause tooth discoloration if taken after all teeth are formed. There were some nasal zinc products that were taken off the market because they were causing damage to the sense of taste. I've never had this happen with any other medication or nutritional supplement but minocycline. ABILIFY® – Otsuka America (aripiprazole) Tablets, ABILIFY® – Bristol-Myers Squibb (aripiprazole) Tablets, ACTIQ® – Cephalon (oral transmucosal fentanyl citrate), ADALAT® CC – Bayer (nifedipine) Extended Release Tablets, ALFERON N INJECTION® – Hemispherx Interferon alfa-n3 (human leukocyte derived), ALPHAGAN® P – Allergan (brimonidine tartrate ophthalmic solution) 0.15%, ALTOPREV? Anything that causes a loss of sense of smell also damages taste as taste and smell are closely linked. High blood sugar may also contribute to transient loss of taste.Altered taste in people with diabetes may also be caused by a change or loss of sense of smell, which affects someone’s … or your stomach acid likes to travel. Today, tetracycline and related antibiotics are not recommended during pregnancy or in young children (under age 8) whose teeth are still forming. Treating the underlying condition that causes your impaired sense of taste can help restore your taste. Rees, T.D. 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